So how can you lay down a run like this in your very own P100D? First, find a safe closed course where the local constabulary won’t write you up for reckless driving. Then ensure your car is running the latest firmware ( release ), and select the Settings menu. Under Acceleration, press and hold the Ludicrous button for five seconds. As with the P90D, this prompts a warp screen of flashing lights followed by a screen that asks, “Are you sure you want to push the limits? This will cause accelerated wear of the motor, gearbox and battery.” The two buttons below are marked, “No, I want my Mommy,” and “Yes, bring it on!” Selecting the latter initiates a process of battery and motor conditioning, wherein the battery temperature is raised slightly and the motors are cooled using the air-conditioning system. It usually takes just a few minutes, longer in extreme ambient temperatures or after repeated runs. You should expect to wait a minimum of 10 minutes in between runs. The readout below the acceleration buttons will say ready when it’s all set. Then you simply hold the brake, promptly tromp the accelerator, and quickly release it to initiate launch-control mode (which is verified on the instrument cluster display). Then firmly hold the brake for a split second while you nail the go pedal. Upon releasing the brake, you will rocket down the strip like Han and Chewbacca jumping to light speed.
In genetics applications, the weights are selected according to the suspected mode of inheritance . For example, in order to test whether allele a is dominant over allele A, the choice t = (1, 1, 0) is locally optimal. To test whether allele a is recessive to allele A, the optimal choice is t = (0, 1, 1). To test whether alleles a and A are codominant , the choice t = (0, 1, 2) is locally optimal. For complex diseases , the underlying genetic model is often unknown. In genome-wide association studies , the additive (or codominant) version of the test is often used.