As a cycle item, from the few people I can find with experience, yes at least twice a day. Some recommend three times, but the way I was bouncing off the walls last night, I say not more than two would make sense. Yes, the few people I found that use it were pre-workout, you are on point. Should have just asked you last month. I purchased it to run with my Clen/T3 dose next week as I am running it very high then and I want some extra protection of muscle. Tell you one thing for certain.... (1) I definitely would not take it on an off day, this is not resting material! (2) I would only take it if joints and tendons are in good order... it just makes you want to move a mountain! It was rocking j223. +1 for having correct input, it is VERY hard to find for this product.