It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
Tren- great medication, which gives excellent results on the path of "solo" to increase muscle mass without the need to be combined with other medications. However, it is a very powerful steroid, and therefore do not exceed the recommended dosage of certain: for acetate - is 50mg per day for enthatate: 300-350mg per week. To test the tolerance of Tren is better to start with a minimum dosage. If the entire rate is not more than six weeks, the need for additional formulations appears; when 6 to 8 weeks, with the need to enter the second week Gonadotropin (500 / 1000ME every 7 days) and stop taking it two weeks after administration cycle. Next, we have to be post-cycle therapy: start 14 days after the last injection or after 3days (if used Tren Acetate). To restore testosterone production take testosterone boosters (4 weeks after the course).