Like other AAS, boldenone is an agonist of the androgen receptor (AR).  The activity of boldenone is mainly anabolic , with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.  Boldenone was synthesized in an attempt to create a long-acting injectable metandienone , for androgen deficiency disorders. Boldenone acts similar to metandienone with fewer adverse androgenic effects. [ medical citation needed ] Although commonly compared to nandrolone , boldenone lacks progesterone receptor interaction and associated progestogenic side effects.
While a truly amazing steroid, Trenbolone-Enanthate is not what we can label the ultimate in-regards to a side-effect friendly nature. Tren carries quite a few possible side-effects, and they are combatable, but it also carries a few that are quite unpredictable. When dosing levels go too high, this can cause such a problem, but more times than not these unpredictable effects will be response related. This is an anabolic steroid that many men will not be able to use; more so than just about any anabolic steroid. Make no mistake, most men will be able to supplement, but some will simply display a poor response. It may not seem fair, and as Trenbolone-Enanthate is such a powerfully effective steroid maybe it's not fair, but life isn't always fair, and there's simply nothing we can do about it. From your first experience with this hormone, you'll know right away if you are such an individual, and this brings us to another point. For your first Tren cycle, you should not supplement with Trenbolone-Enanthate; instead, you must choose the Acetate version. If you happen to be one of the unlucky few, the last thing you want is the large ester version in your system. If the unpredictable side-effects hit, you'll need to discontinue use immediately, and if you're using the Acetate version they'll fade away in a few days; however, if you're using the Enanthate version it's going to take a few weeks, and that can be miserable.