Testosterone propionate was introduced in 1937 by Schering AG in Germany under the brand name Testoviron .  It was the first ester of testosterone to be introduced,  and was the major form of testosterone used medically before 1960.  In the 1950s, longer-acting testosterone esters like testosterone enanthate and testosterone cypionate were introduced and superseded testosterone propionate.  Although rarely used nowadays due to its short duration,  testosterone propionate remains medically available and is still marketed in the United States .  
Testosterone Propionate also converts to both Estrogen (through Aromatization) and Dihydrotestosterone (through 5a-reduction). Most of the side effects people experience with testosterone use is actually from it’s conversion to these two substrates. Thus, hair loss , water retention, acne, and other side effects are possible with use of this drug. Conversion to these hormones is also responsible for some of testosterone’s ability to build muscle; therefore when many side effects are avoided with the use of ancillary compounds, some of the muscle building properties are also stunted.