Overdose Symptoms of overdose strofantinom-T varied. Cardio-vascular system: arrhythmia, including bradycardia, AV-block, ventricular tachycardia or extrasystole, ventricular fibrillation. On the part of the digestive tract: anorexia, nausea, vomiting, diarrhea. On the part of the central nervous system and sensory organs: headache , fatigue. dizziness, rarely – staining the surrounding objects in green and yellow colors, a sense of flicker flies before his eyes, blurred vision, scotoma, macro- and micropsia: very rarely confusion, sinkoialnye state. With the development of glycoside intoxication drug buy testosterone propionate should be discontinued; assign the patient potassium supplements, parenteral administration unitiola, symptomatic therapy.
Inclusion of lb of calcium propionate in the prefresh and fresh ration, provides a extra daily dose of propionate which reduces both subclinical and clinical ketosis. Propionate is used as a glucose source to make milk lactose (or milk sugar). Propionate is also used at the liver to convert acetate (from mobilized fat) to energy. Some researchers believe that calcium propionate mainly spares dietary protein from being metabolized to glucose. Thus, with the addition of calcium propionate in the diet, more amino acids are available for conversion to milk protein and total milk production increases.
No metabolites of fluticasone propionate were detected in an in vitro study of radiolabeled fluticasone propionate incubated in a human skin homogenate. The total blood clearance of systemically absorbed fluticasone propionate averages 1,093 mL/min (range, 618 to 1,702 mL/min) after a 1-mg intravenous dose, with renal clearance accounting for less than % of the total. Fluticasone propionate is metabolized in the liver by cytochrome P450 3A4-mediated hydrolysis of the 5- fluoromethyl carbothioate grouping. This transformation occurs in 1 metabolic step to produce the inactive17-ÃŸ-carboxylic acid metabolite, the only known metabolite detected in man. This metabolite has approximately 2,000 times less affinity than the parent drug for the glucocorticoid receptor of human lung cytosol in vitro and negligible pharmacological activity in animal studies. Other metabolites detected in vitro using cultured human hepatoma cells have not been detected in man.